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DESCRIPTION OF DRUG XYLOCAINE

Сontents:
Xylocaine, instruction manual
Pharmacological action of xylocaine
Indications for admission xylocaine
Dosing regimen xylocaine
Interaction xylocaine
Side effects xylocaine
Contraindications when using xylocaine

 

Xylocaine, instruction manual

International name. Lidocain. Structure and Composition Xylocain. Active ingredient - lidocaine hydrochloride. Fluid 1% 20mlv ampoules of 5 pcs. in packaging. Solution 2% -20 ml in 5 pcs. in container. Structure 2% - 2 ml in 100 pieces container. Xylocain-adrenaline 2% -2 ml in 100 pcs. in packaging. Powder for 0.5%, 1% and 2% solutions Xylocain with epinephrine 1:200,000 in breeding.

Pharmacological action of xylocaine

antiarrhythmic . Does not change sensuality sinoatrial node , has little effect on the conductivity and contractility . When administered intravenously, acts fast and little ( 10-20 minutes). Mechanism of local anesthetic effect is to stabilize the neuronal membrane , reducing its permeability to sodium ions , thus preventing potential operation and conduction of impulses . Fast hydrolyzed under mildly alkaline sphere fabrics and after a short latency period is valid for 60-90 minutes. When inflammation (tissue acidosis) anesthetic initiative decreases. Effective with all kinds of local anesthesia. Dilates blood vessels . Not irritating to the tkani.Dostatochno soon is absorbed by the mucous membranes of the upper respiratory tract or oral cavity. Stable concentration in the blood is established through 4-5 hours with continuous intravenous administration. Easy passes through gistogematicalkie barriers, including GEB. Crosses the placenta . Soon and almost completely metabolized in the liver .

Indications for admission xylocaine

Terminal, infiltration, conduction, spinal (epidural) anesthesia in surgery, ophthalmology, dentistry, otorhinolaryngology. Lidocaine do for blockade of peripheral nerves and ganglia. Ventricular arrhythmias form (tachycardia and ventricular premature beats) and mostly to prevent ventricular fibrillation in acute stage of myocardial infarction.

Dosing regimen xylocaine

Infiltration anesthesia for total 0.25% the solution should not exceed 2000 ml and 0.5% solution - 500ml. For conduction anesthesia is administered to 50ml 0.5-1-2% solution. As the antiarrhythmic agents are administered intravenously 60 mg over 3-4 minutes, followed by intravenous infusion of the solution containing 2 mg | ml of lidocaine at a rate 4 mg | min.

Interaction xylocaine

sodium), hypnotics and sedatives tools on the respiratory center, weakens the cardiotonic influence digitoksina deepens miorelaksaciu caused kurarepodobnymi drugs

Side effects xylocaine

Lidocaine is usually not bad, but it may idiosyncrasy. In case of overdose can occur negative, nausea, irritability, visual disturbances, tremors, convulsions and even parking breathing. With rapid intravenous lidocaine may decrease blood pressure up to the collapse.

Contraindications when using xylocaine

Master sensitivity local anesthetics of the amide series.

 

Сontents:
Xylocaine, instruction manual.
Pharmacological action of xylocaine
Indications for admission xylocaine
Dosing regimen xylocaine
Interaction xylocaine
Side effects xylocaine
Contraindications when using xylocaine

 

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